Acaricidal activity of extract from Eupatorium adenophorum against thePsoroptes cuniculiandSarcoptes scabieiin vitro
Nong X, Fang CL, Wang JH, Gu XB, Yang DY, Liu TF, Fu Y, Zhang RH, Zheng WP, Peng XR, Wang SX, Yang GY.
Abstract
The possibleacaricidalactivityofEupatoriumadenophorumwas analyzed using extracts created by water decocting, ethanol thermal circumfluence, and steam distillation. The toxic effect of eachextractwas testedagainstPsoroptescuniculiandSarcoptesscabieiinvitro. Ethanol thermal circumfluenceextracthad strong toxicityagainstmites, killing allS.scabieiat 0.5 and 1.0 g/ml (w/v) concentration, while 1g/mlextractwas also found to kill allP.cuniculiwithin a 4-h period. Similarly, 0.25, 0.5 and 1.0 g/ml concentration ofextracthad strong toxicityagainstS.scabiei,with median lethal time (LT(50)) values at 0.866, 0.785 and 0.517 h, respectively. 0.5 g/ml and 1g/ml showed strongacaricidalactionagainstP.cuniculi;the LT(50) values were 0.93 h and 1.29 h, respectively. The median lethal concentration (LC(50)) values were 0.22 g/ml for Scabies mite and 0.64 g/ml forP.cuniculiin 1h. The results indicated thatE.adenophorumcontains potentacaricidalingredients; as a first step in the potential development of novel drugs, it may provide newacaricidalcompounds for the effective control of animal acariasis.
Copyright © 2011 Elsevier B.V. All rights reserved.
Vet Parasitol.2012 Jun 8;187(1-2):345-9. doi: 10.1016/j.vetpar.2011.12.015. Epub 2011 Dec 23.
Read full text:http://www.sciencedirect.com/science/article/pii/S0304401711008533
